The evolutionary rate dynamically tracks changes in HIV-1 epidemics: application of a simple method for optimizing the evolutionary rate in phylogenetic trees with longitudinal data

Large sequence datasets provide an opportunity to investigate the dynamics of pathogen epidemics. Thus, a fast method to estimate the evolutionary rate from large and numerous phylogenetic trees becomes necessary. Based on minimizing tip height variances, we optimize the root in a given phylogenetic...

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Hauptverfasser: Berry, Irina Maljkovic, Athreya, Gayathri, Kothari, Moulik, Daniels, Marcus, Bruno, William J., Korber, Bette, Kuiken, Carla, Ribeiro, Ruy M., Leitner, Thomas
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2009
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3053002/
https://ncbi.nlm.nih.gov/pubmed/21352769
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.epidem.2009.10.003
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