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PEGYLATED INTERFERON ALPHA TARGETS WNT SIGNALING BY INDUCING NUCLEAR EXPORT OF β-CATENIN
BACKGROUND & AIMS: Pegylated-Interferon-α2a (peg-IFN), a first line therapy for Hepatitis C virus (HCV) patients, also impacts recurrence of hepatocellular carcinoma (HCC). Wnt pathway activation due to β-catenin gene mutations contributes to the development of a significant subset of HCC. Here,...
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| Main Authors: | , , |
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| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
2010
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3052972/ https://ncbi.nlm.nih.gov/pubmed/21093092 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jhep.2010.07.020 |
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