Loss of Object Recognition Memory Produced by Extended Access to Methamphetamine Self-Administration is Reversed by Positive Allosteric Modulation of Metabotropic Glutamate Receptor 5

Chronic methamphetamine (meth) abuse can lead to persisting cognitive deficits. Here, we utilized a long-access meth self-administration (SA) protocol to assess recognition memory and metabotropic glutamate receptor (mGluR) expression, and the possible reversal of cognitive impairments with the mGlu...

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Autors principals: Reichel, Carmela M, Schwendt, Marek, McGinty, Jacqueline F, Olive, M Foster, See, Ronald E
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group 2011
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Original Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3052905/
https://ncbi.nlm.nih.gov/pubmed/21150906
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/npp.2010.212
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