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Regulating a master regulator: Establishing tissue-specific gene expression in skeletal muscle

MyoD is a master regulator of the skeletal muscle gene expression program. ChIP-Seq analysis has recently revealed that MyoD binds to a large number of genomic loci in differentiating myoblasts, yet only activates transcription at a subset of these genes. Here we discuss recent data suggesting that...

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Detalhes bibliográficos
Main Authors: Aziz, Arif, Liu, Qi-Cai, Dilworth, F Jeffrey
Formato: Artigo
Idioma:Inglês
Publicado em: Landes Bioscience 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3052885/
https://ncbi.nlm.nih.gov/pubmed/20716948
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/epi.5.8.13045
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