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Regulating a master regulator: Establishing tissue-specific gene expression in skeletal muscle
MyoD is a master regulator of the skeletal muscle gene expression program. ChIP-Seq analysis has recently revealed that MyoD binds to a large number of genomic loci in differentiating myoblasts, yet only activates transcription at a subset of these genes. Here we discuss recent data suggesting that...
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| Main Authors: | , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Landes Bioscience
2010
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3052885/ https://ncbi.nlm.nih.gov/pubmed/20716948 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/epi.5.8.13045 |
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