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The effect of charge-reversal amphiphile spacer composition on DNA and siRNA delivery
A series of charge-reversal amphiphiles with different spacers separating the head group from the hydrophobic chains are described for delivery of DNA and siRNA. Among them, the amphiphiles possessing a glycine spacer (e.g., B-GlyGly) showed effective DNA transfection in CHO and NIH 3T3 cells as wel...
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Main Authors: | , , , , |
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Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
2010
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3052776/ https://ncbi.nlm.nih.gov/pubmed/20433165 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bc9005464 |
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