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Modeling vesicle traffic reveals unexpected consequences for Cdc42p-mediated polarity establishment

BACKGROUND: Polarization in yeast has been proposed to involve a positive feedback loop whereby the polarity regulator Cdc42p orients actin cables, which deliver vesicles carrying Cdc42p to the polarization site. Previous mathematical models treating Cdc42p traffic as a membrane-free flux suggested...

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Autori principali: Layton, Anita T., Savage, Natasha S., Howell, Audrey S., Carroll, Susheela Y., Drubin, David G., Lew, Daniel J.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2011
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3052744/
https://ncbi.nlm.nih.gov/pubmed/21277209
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cub.2011.01.012
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