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The N-terminus of Bunyamwera orthobunyavirus NSs protein is essential for interferon antagonism

Bunyamwera virus NSs protein is involved in the inhibition of cellular transcription and the interferon (IFN) response, and it interacts with the Med8 component of Mediator. A spontaneous mutant of a recombinant NSs-deleted Bunyamwera virus (rBUNdelNSs2) was identified and characterized. This mutant...

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Detalhes bibliográficos
Main Authors: van Knippenberg, Ingeborg, Carlton-Smith, Charlie, Elliott, Richard M.
Formato: Artigo
Idioma:Inglês
Publicado em: Society for General Microbiology 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3052537/
https://ncbi.nlm.nih.gov/pubmed/20427562
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1099/vir.0.021774-0
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