Induction of mucosal and systemic antibody and T-cell responses following prime–boost immunization with novel adjuvanted human immunodeficiency virus-1-vaccine formulations

As sexual transmission of human immunodeficiency virus-1 (HIV-1) occurs via the mucosa, an ideal HIV-1 vaccine should induce both mucosal and systemic immunity. We therefore sought to evaluate the induction of mucosal responses using a DNA env prime–gp120 protein boost approach in which sequential n...

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Hlavní autoři: Cristillo, Anthony D., Ferrari, Maria Grazia, Hudacik, Lauren, Lewis, Brad, Galmin, Lindsey, Bowen, Britany, Thompson, DeVon, Petrovsky, Nikolai, Markham, Phillip, Pal, Ranajit
Médium: Artigo
Jazyk:Inglês
Vydáno: Society for General Microbiology 2011
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Animal
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3052530/
https://ncbi.nlm.nih.gov/pubmed/21169215
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1099/vir.0.023242-0
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