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A negative charge in transmembrane segment 1 of domain II of the cockroach sodium channel is critical for channel gating and action of pyrethroid insecticides

Voltage-gated sodium channels are the primary target of pyrethroids, an important class of synthetic insecticides. Pyrethroids bind to a distinct receptor site on sodium channels and prolong the open state by inhibiting channel deactivation and inactivation. Recent studies have begun to reveal sodiu...

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Bibliografski detalji
Glavni autori: Du, Yuzhe, Song, Weizhong, Groome, James R., Nomura, Yoshiko, Luo, Ningguang, Dong, Ke
Format: Artigo
Jezik:Inglês
Izdano: 2010
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3052377/
https://ncbi.nlm.nih.gov/pubmed/20561903
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.taap.2010.05.016
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