Detection of normal B-cell precursors that give rise to colonies producing both kappa and lambda light immunoglobulin chains.
The pre-B-cell cloning assay is an in vitro differentiation system in which B-lymphocyte precursors expand and generate colonies containing immunoglobulin-secreting cells. Analysis of surface characteristics, growth requirements, and kinetics suggested that these cells represent early stages of the...
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| Publicado no: | Proc Natl Acad Sci U S A |
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| Principais autores: | , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
1987
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC305232/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/3110779/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.84.14.4989 |
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