Phosphonium labeling for increasing metabolomic coverage of neutral lipids using electrospray ionization mass spectrometry

Mass spectrometry has become an indispensable tool for the global study of metabolites (metabolomics), primarily using electrospray ionization mass spectrometry (ESI-MS). However, many important classes of molecules such as neutral lipids do not ionize well by ESI and go undetected. Chemical derivat...

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Main Authors: Woo, Hin-Koon, Go, Eden P., Hoang, Linh, Trauger, Sunia A., Bowen, Benjamin, Siuzdak, Gary, Northen, Trent R.
Format: Artigo
Sprog:Inglês
Udgivet: 2009
Fag:
Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3052201/
https://ncbi.nlm.nih.gov/pubmed/19449318
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/rcm.4076
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