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Differences in allergen-induced T cell activation between allergic asthma and rhinitis: Role of CD28, ICOS and CTLA-4

BACKGROUND: Th2 cell activation and T regulatory cell (Treg) deficiency are key features of allergy. This applies for asthma and rhinitis. However with a same atopic background, some patients will develop rhinitis and asthma, whereas others will display rhinitis only. Co-receptors are pivotal in det...

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Detalhes bibliográficos
Main Authors: Botturi, Karine, Lacoeuille, Yannick, Cavaillès, Arnaud, Vervloet, Daniel, Magnan, Antoine
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2011
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3051906/
https://ncbi.nlm.nih.gov/pubmed/21356099
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1465-9921-12-25
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