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Effects of rasagiline, its metabolite aminoindan and selegiline on glutamate receptor mediated signalling in the rat hippocampus slice in vitro

BACKGROUND: Rasagiline, a new drug developed to treat Parkinson's disease, is known to inhibit monoamine oxidase B. However, its metabolite R-(-)-aminoindan does not show this kind of activity. The present series of in vitro experiments using the rat hippocampal slice preparation deals with eff...

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Detalhes bibliográficos
Main Authors: Dimpfel, W, Hoffmann, JA
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3051903/
https://ncbi.nlm.nih.gov/pubmed/21338509
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2210-11-2
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