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Random mutagenesis screening indicates the absence of a separate H(+)-sensor in the pH-sensitive Kir channels
Several inwardly-rectifying (Kir) potassium channels (Kir1.1, Kir4.1 and Kir4.2) are characterised by their sensitivity to inhibition by intracellular H(+) within the physiological range. The mechanism by which these channels are regulated by intracellular pH has been the subject of intense scrutiny...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Landes Bioscience
2010
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3051873/ https://ncbi.nlm.nih.gov/pubmed/20699659 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/chan.4.5.13006 |
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