Hepatitis B virus produced by transfected Hep G2 cells causes hepatitis in chimpanzees.

We have reported that clonal cells derived from Hep G2 cells transfected with a plasmid containing hepatitis B virus (HBV) DNA secrete spherical and filamentous forms of hepatitis B surface antigen (HBsAg), core particles, and virions into the culture medium. Here we describe the development of typi...

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Veröffentlicht in:	Proc Natl Acad Sci U S A
Hauptverfasser:	Acs, G, Sells, M A, Purcell, R H, Price, P, Engle, R, Shapiro, M, Popper, H
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	National Academy of Sciences 1987
Schlagworte:	Research Article
Online-Zugang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC305146/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2885842/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.84.13.4641
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