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Mitochondrial dysfunction in distal axons contribute to HIV sensory neuropathy
OBJECTIVE: Accumulation of mitochondrial DNA (mtDNA) damage has been associated with aging and abnormal oxidative metabolism. We hypothesized that in human immunodeficiency virus associated sensory neuropathy (HIV-SN), damaged mtDNA accumulates in distal nerve segments and that a spatial pattern of...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2010
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3051401/ https://ncbi.nlm.nih.gov/pubmed/21280080 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/ana.22150 |
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