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Induction of cytotoxicity in resting human T lymphocytes bound to tumor cells by antibody heteroconjugates.

An in vitro model for peripheral human T-cell activation and resultant tumor cell killing is described. Cytotoxic T lymphocytes may be generated from resting lymphocytes by incubation of human peripheral blood mononuclear cells for 3 days with the anti-CD3 monoclonal antibody OKT3. Cytotoxicity in p...

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Bibliografiske detaljer
Main Authors: Jung, G, Ledbetter, J A, Müller-Eberhard, H J
Format: Artigo
Sprog:Inglês
Udgivet: 1987
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC305140/
https://ncbi.nlm.nih.gov/pubmed/3110771
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