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Induction of cytotoxicity in resting human T lymphocytes bound to tumor cells by antibody heteroconjugates.
An in vitro model for peripheral human T-cell activation and resultant tumor cell killing is described. Cytotoxic T lymphocytes may be generated from resting lymphocytes by incubation of human peripheral blood mononuclear cells for 3 days with the anti-CD3 monoclonal antibody OKT3. Cytotoxicity in p...
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| Publicado no: | Proc Natl Acad Sci U S A |
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| Main Authors: | , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
1987
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC305140/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/3110771/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.84.13.4611 |
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