Tetramethylphenylenediamine protects the isolated heart against ischaemia-induced apoptosis and reperfusion-induced necrosis

BACKGROUND AND PURPOSE: Cytochrome c when released from mitochondria into cytosol triggers assembly of the apoptosome resulting in caspase activation. Recent evidence suggests that reduced cytochrome c is unable to activate the caspase cascade. In this study, we investigated whether a chemical reduc...

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Autori principali: Barauskaite, Jurgita, Grybauskiene, Regina, Morkuniene, Ramune, Borutaite, Vilmante, Brown, Guy C
Natura: Artigo
Lingua:Inglês
Pubblicazione: Blackwell Science Inc 2011
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Research Papers
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3051385/
https://ncbi.nlm.nih.gov/pubmed/21077848
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1476-5381.2010.01110.x
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