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Human T-cell lymphotropic virus IIIB glycoprotein (gp120) bound to CD4 determinants on normal lymphocytes and expressed by infected cells serves as target for immune attack.

The lymphocyte differentiation antigen CD4 serves as a receptor for human retroviruses associated with acquired immunodeficiency syndrome (AIDS) through its interaction with the major envelope virion glycoprotein, gp120, which is also expressed on the surface of infected cells. In these experiments,...

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Udgivet i:Proc Natl Acad Sci U S A
Principais autores: Lyerly, H K, Matthews, T J, Langlois, A J, Bolognesi, D P, Weinhold, K J
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 1987
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC305138/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/3037522/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.84.13.4601
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