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Microarray analysis of nemorosone-induced cytotoxic effects on pancreatic cancer cells reveals activation of the unfolded protein response (UPR)

BACKGROUND AND PURPOSE: Pancreatic cancer is one of the leading cancer-related causes of death due to high chemo-resistance and fast metastasation. Nemorosone, a polycyclic polyprenylated acylphloroglucinol, has recently been identified as a promising anticancer agent. Here, we examine its growth-in...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Holtrup, Frank, Bauer, Andrea, Fellenberg, Kurt, Hilger, Ralf A, Wink, Michael, Hoheisel, Jörg D
Format: Artigo
Sprache:Inglês
Veröffentlicht: Blackwell Science Inc 2011
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3051378/
https://ncbi.nlm.nih.gov/pubmed/21091652
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1476-5381.2010.01125.x
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