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NFKBIZ polymorphisms and susceptibility to pneumococcal disease in European and African populations
The proinflammatory transcription factor nuclear factor-kappaB (NF-κB) plays a central role in host defence against pneumococcal disease. Both rare mutations and common polymorphisms in the NFKBIA gene encoding the NF-κB inhibitor IκB-α associate with susceptibility to bacterial disease, but the pos...
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Asıl Yazarlar: | , , , , , , , , , , , , , |
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Materyal Türü: | Artigo |
Dil: | Inglês |
Baskı/Yayın Bilgisi: |
2009
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Konular: | |
Online Erişim: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3051152/ https://ncbi.nlm.nih.gov/pubmed/19798075 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/gene.2009.76 |
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