Cloning and heterologous expression of a gene cluster for the biosynthesis of tetracenomycin C, the anthracycline antitumor antibiotic of Streptomyces glaucescens.

Eitemau Tebyg

• Anthracycline metabolites of tetracenomycin C-nonproducing Streptomyces glaucescens mutants.
  gan: Yue, S, et al.
  Cyhoeddwyd: (1986)
• Transcriptional analysis of the Streptomyces glaucescens tetracenomycin C biosynthesis gene cluster.
  gan: Decker, H, et al.
  Cyhoeddwyd: (1993)
• Isolation of tetracenomycin C-nonproducing Streptomyces glaucescens mutants.
  gan: Motamedi, H, et al.
  Cyhoeddwyd: (1986)
• Nucleotide sequences and heterologous expression of tcmG and tcmP, biosynthetic genes for tetracenomycin C in Streptomyces glaucescens.
  gan: Decker, H, et al.
  Cyhoeddwyd: (1993)
• The tcmVI region of the tetracenomycin C biosynthetic gene cluster of Streptomyces glaucescens encodes the tetracenomycin F1 monooxygenase, tetracenomycin F2 cyclase, and, most likely, a second cyclase.
  gan: Summers, R G, et al.
  Cyhoeddwyd: (1993)