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Genome-wide identification and annotation of HIF-1α binding sites in two cell lines using massively parallel sequencing

We identified 531 and 616 putative HIF-1α target sites by ChIP-Seq in the cancerous cell line DLD-1 and the non-cancerous cell line TIG-3, respectively. We also examined the positions and expression levels of transcriptional start sites (TSSs) in these cell lines using our TSS-Seq method. We observe...

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Main Authors: Tanimoto, Kousuke, Tsuchihara, Katsuya, Kanai, Akinori, Arauchi, Takako, Esumi, Hiroyasu, Suzuki, Yutaka, Sugano, Sumio
Formato: Artigo
Idioma:Inglês
Publicado: Springer Netherlands 2011
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3051044/
https://ncbi.nlm.nih.gov/pubmed/22132063
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s11568-011-9150-9
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