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Genetic and Functional Role of TNF-alpha in the Development Trypanosoma cruzi Infection

TNF-alpha plays an important role in trypanocidal mechanisms and is related to tissue injury. This cytokine has been detected in the heart of human chagasic patients where it is associated with tissue damage. This study investigated whether TNF-alpha levels and the presence of genetic polymorphisms...

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Dettagli Bibliografici
Autori principali: Pissetti, Cristina Wide, Correia, Dalmo, de Oliveira, Rafael Faria, Llaguno, Maurício Manoel, Balarin, Marly Aparecida Spadotto, Silva-Grecco, Roseane Lopes, Rodrigues, Virmondes
Natura: Artigo
Lingua:Inglês
Pubblicazione: Public Library of Science 2011
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3050938/
https://ncbi.nlm.nih.gov/pubmed/21408088
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pntd.0000976
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