Exceptional Diversity, Maintenance of Polymorphism, and Recent Directional Selection on the APL1 Malaria Resistance Genes of Anopheles gambiae

The three-gene APL1 locus encodes essential components of the mosquito immune defense against malaria parasites. APL1 was originally identified because it lies within a mapped QTL conferring the vector mosquito Anopheles gambiae natural resistance to the human malaria parasite, Plasmodium falciparum...

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Detalhes bibliográficos
Main Authors: Rottschaefer, Susan M., Riehle, Michelle M., Coulibaly, Boubacar, Sacko, Madjou, Niaré, Oumou, Morlais, Isabelle, Traoré, Sekou F., Vernick, Kenneth D., Lazzaro, Brian P.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2011
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3050937/
https://ncbi.nlm.nih.gov/pubmed/21408087
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pbio.1000600
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