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Epidermal Growth Factor and Estrogen Act by Independent Pathways to Additively Promote the Release of the Angiogenic Chemokine CXCL8 by Breast Tumor Cells

The tumor microenvironment contains multiple cancer-supporting factors, whose joint activities promote malignancy. Here, we show that epidermal growth factor (EGF) and estrogen upregulate in an additive manner the transcription and the secretion of the angiogenic chemokine CXCL8 (interleukin 8 [IL-8...

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主要な著者: Haim, Karin, Weitzenfeld, Polina, Meshel, Tsipi, Ben-Baruch, Adit
フォーマット: Artigo
言語:Inglês
出版事項: Neoplasia Press Inc. 2011
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC3050866/
https://ncbi.nlm.nih.gov/pubmed/21390186
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