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Isoform-selective physical coupling of TRPC3 channels to IP(3) receptors in smooth muscle cells regulates arterial contractility

RATIONALE: Inositol 1,4,5-trisphosphate (IP(3))-induced vasoconstriction can occur independently of intracellular Ca(2+) release and via IP(3) receptor (IP(3)R) and canonical transient receptor potential (TRPC) channel activation, but functional signaling mechanisms mediating this effect are unclear...

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Bibliographic Details
Main Authors: Adebiyi, Adebowale, Zhao, Guiling, Narayanan, Damodaran, Thomas, Candice M., Bannister, John P., Jaggar, Jonathan H.
Format: Artigo
Language:Inglês
Published: 2010
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3050672/
https://ncbi.nlm.nih.gov/pubmed/20378853
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/CIRCRESAHA.110.216804
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