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[2+2] Cycloaddition of ketenes with ynamides. A general method for the synthesis of 3-aminocyclobutenone derivatives

Ynamides react with ketenes in [2+2] cycloadditions leading to a variety of substituted 3-aminocyclobut-2-en-1-ones. The ynamides employed in these reactions are readily available via the copper-promoted N-alkynylation of carbamates and sulfonamides with alkynyl bromides and iodides. The scope of th...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Kohnen, Amanda L., Mak, Xiao Yin, Lam, Tin Yiu, Dunetz, Joshua R., Danheiser, Rick L.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: 2006
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC3050601/
https://ncbi.nlm.nih.gov/pubmed/21394235
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.tet.2005.11.088
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