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Nitric oxide inhibition of Drp1-mediated mitochondrial fission is critical for myogenic differentiation

During myogenic differentiation the short mitochondria of myoblasts change into the extensively elongated network observed in myotubes. The functional relevance and the molecular mechanisms driving the formation of this mitochondrial network are unknown. We now show that mitochondrial elongation is...

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Detalhes bibliográficos
Main Authors: De Palma, C, Falcone, S, Pisoni, S, Cipolat, S, Panzeri, C, Pambianco, S, Pisconti, A, Allevi, R, Bassi, MT, Cossu, G, Pozzan, T, Moncada, S, Scorrano, L, Brunelli, S, Clementi, E
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3050583/
https://ncbi.nlm.nih.gov/pubmed/20467441
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cdd.2010.48
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