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Modeling Inducible Human Tissue Neoplasia Identifies an Extracellular Matrix Interaction Network Involved in Cancer Progression

To elucidate mechanisms of cancer progression, we generated inducible human neoplasia in 3-dimensionally intact epithelial tissue. Gene expression profiling of both epithelia and stroma at specific time points during tumor progression revealed sequential enrichment of genes mediating discrete biolog...

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Detalhes bibliográficos
Main Authors: Reuter, Jason A., Ortiz-Urda, Susana, Kretz, Markus, Garcia, John, Scholl, Florence A., Pasmooij, Anna M.G., Cassarino, David, Chang, Howard Y., Khavari, Paul A.
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3050547/
https://ncbi.nlm.nih.gov/pubmed/19477427
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ccr.2009.04.002
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