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Mannose-binding lectin deficiency influences innate and antigen-presenting functions of blood myeloid dendritic cells

Mannose-binding lectin (MBL) is a serum lectin that plays a significant role in innate host defence. Individuals with mutations in exon 1 of the MBL2 gene have reduced MBL ligand binding and complement activation function and increased incidence of infection. We proposed that, during infection, MBL...

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Autors principals: Dean, Melinda M, Flower, Robert L, Eisen, Damon P, Minchinton, Robyn M, Hart, Derek N J, Vuckovic, Slavica
Format: Artigo
Idioma:Inglês
Publicat: Blackwell Science Inc 2011
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3050452/
https://ncbi.nlm.nih.gov/pubmed/21091907
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1365-2567.2010.03365.x
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