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The effects of maribavir on the autophosphorylation of ganciclovir resistant mutants of the cytomegalovirus UL97 protein

BACKGROUND: The UL97 protein kinase of human cytomegalovirus phosphorylates the antiviral drug ganciclovir and is the target of maribavir action. A detailed enzyme kinetic analysis of maribavir on the various enzymatic functions of wild type and ganciclovir resistant forms of UL97 is required. METHO...

詳細記述

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書誌詳細
主要な著者: Shannon-Lowe, Claire D, Emery, Vincent C
フォーマット: Artigo
言語:Inglês
出版事項: BioMed Central 2010
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC3050433/
https://ncbi.nlm.nih.gov/pubmed/21429239
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/2042-4280-1-4
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