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Synthetic peptide antagonists of glucagon.

Several glucagon analogs were synthesized in an effort to find derivatives that would bind with high affinity to the glucagon receptor of rat liver membranes but would not activate membrane-bound adenylate cyclase and, therefore, would serve as antagonists of the hormone. Measurements on a series of...

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Autors principals: Unson, C G, Andreu, D, Gurzenda, E M, Merrifield, R B
Format: Artigo
Idioma:Inglês
Publicat: 1987
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC305026/
https://ncbi.nlm.nih.gov/pubmed/3035568
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