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Association of left atrial endothelin-1 with atrial rhythm, size and fibrosis in patients with structural heart disease

BACKGROUND: Atrial fibrillation (AF) promotes atrial remodeling and can develop secondary to heart failure (HF) or mitral valve disease. Cardiac endothelin-1 (ET-1) expression responds to wall stress, and can promote myocyte hypertrophy and interstitial fibrosis. We tested the hypothesis that atrial...

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Detalhes bibliográficos
Main Authors: Mayyas, Fadia, Niebauer, Mark, Zurick, Andrew, Barnard, John, Gillinov, A. Marc, Chung, Mina K., Van Wagoner, David R.
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3050013/
https://ncbi.nlm.nih.gov/pubmed/20495015
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/CIRCEP.109.924985
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