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Differential involvement of striato- and cerebello-thalamo-cortical pathways in tremor-and akinetic/rigid-predominant Parkinson's disease

Parkinson's disease (PD) presents clinically with varying degrees of resting tremor, rigidity, and bradykinesia. For decades, striatal-thalamo-cortical (STC) dysfunction has been implied in bradykinesia and rigidity, but does not explain resting tremor in PD. To understand the roles of cerebell...

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Main Authors: Lewis, Mechelle M., Du, Guangwei, Sen, Suman, Kawaguchi, Atsushi, Truong, Young, Lee, Seonjoo, Mailman, Richard B., Huang, Xuemei
格式: Artigo
語言:Inglês
出版: 2011
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC3049982/
https://ncbi.nlm.nih.gov/pubmed/21211551
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neuroscience.2010.12.060
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