Hexapeptide libraries for enhanced protein PTM identification and relative abundance profiling in whole human saliva

Dynamic range compression (DRC) by hexapeptide libraries increases MS/MS-based identification of lower-abundance proteins in complex mixtures. However, two unanswered questions impede fully realizing DRC’s potential in shotgun proteomics. First, does DRC enhance identification of post-translationall...

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Hauptverfasser: Bandhakavi, Sricharan, Van Riper, Susan K, Tawfik, Pierre N, Stone, Matthew D, Haddad, Tufia, Rhodus, Nelson L., Carlis, John V., Griffin, Timothy J
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2011
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3049962/
https://ncbi.nlm.nih.gov/pubmed/21142092
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/pr100857t
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