Tight Junction Defects in Atopic Dermatitis

BACKGROUND: Atopic dermatitis (AD) is characterized by dry skin and a hyperreactive immune response to allergens, two cardinal features that are caused in part by epidermal barrier defects. Tight junctions (TJ) reside immediately below the stratum corneum and regulate the selective permeability of t...

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Detalhes bibliográficos
Main Authors: De Benedetto, Anna, Rafaels, Nicholas M., McGirt, Laura Y., Ivanov, Andrei I., Georas, Steve N., Cheadle, Chris, Berger, Alan E., Zhang, Kunzhong, Vidyasagar, Sadasivan, Yoshida, Takeshi, Boguniewicz, Mark, Hata, Tissa, Schneider, Lynda C., Hanifin, Jon M., Gallo, Richard L., Novak, Natalija, Weidinger, Stephan, Beaty, Terri H., Leung, Donald Y., Barnes, Kathleen C., Beck, Lisa A.
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3049863/
https://ncbi.nlm.nih.gov/pubmed/21163515
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jaci.2010.10.018
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