Tight Junction Defects in Atopic Dermatitis

BACKGROUND: Atopic dermatitis (AD) is characterized by dry skin and a hyperreactive immune response to allergens, two cardinal features that are caused in part by epidermal barrier defects. Tight junctions (TJ) reside immediately below the stratum corneum and regulate the selective permeability of t...

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Main Authors: De Benedetto, Anna, Rafaels, Nicholas M., McGirt, Laura Y., Ivanov, Andrei I., Georas, Steve N., Cheadle, Chris, Berger, Alan E., Zhang, Kunzhong, Vidyasagar, Sadasivan, Yoshida, Takeshi, Boguniewicz, Mark, Hata, Tissa, Schneider, Lynda C., Hanifin, Jon M., Gallo, Richard L., Novak, Natalija, Weidinger, Stephan, Beaty, Terri H., Leung, Donald Y., Barnes, Kathleen C., Beck, Lisa A.
Formáid: Artigo
Teanga:Inglês
Foilsithe: 2010
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Article
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3049863/
https://ncbi.nlm.nih.gov/pubmed/21163515
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jaci.2010.10.018
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