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Assessing the Biological Significance of Gene Expression Signatures and Co-Expression Modules by Studying Their Network Properties

Microarray experiments have been extensively used to define signatures, which are sets of genes that can be considered markers of experimental conditions (typically diseases). Paradoxically, in spite of the apparent functional role that might be attributed to such gene sets, signatures do not seem t...

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Autors principals: Minguez, Pablo, Dopazo, Joaquin
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2011
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3049771/
https://ncbi.nlm.nih.gov/pubmed/21408226
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0017474
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