Transmission in NFS/N mice of the heritable spongiform encephalopathy associated with the gray tremor mutation.

It has been shown that the autosomal recessive mutation, gray tremor (gt) was associated in the homozygous state (gt/gt) with a rapidly fatal spongiform encephalopathy. Heterozygotes (+/gt) developed mild asymptomatic spongiform brain lesions as did recipient inbred mice inoculated with gt/gt brain...

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Detalhes bibliográficos

Publicado no:	Proc Natl Acad Sci U S A
Principais autores:	Hoffman, P M, Rohwer, R G, MacAuley, C, Bilello, J A, Hartley, J W, Morse, H C
Formato:	Artigo
Idioma:	Inglês
Publicado em:	National Academy of Sciences 1987
Assuntos:	Research Article
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC304977/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/3473486/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.84.11.3866
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