CXC receptor-4 mRNA silencing abrogates CXCL12-induced migration of colorectal cancer cells

BACKGROUND: Interactions between CXCR4 and its ligand CXCL12 have been shown to be involved in cancer progression in colorectal cancer (CRC). We performed a comparative CXCL12/CXCR4 expression analysis and assessed the effect of external CXCL12 stimulation on migration of CRC cells without and with...

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Hauptverfasser: Rubie, Claudia, Frick , Vilma O, Ghadjar, Pirus, Wagner, Mathias, Justinger, Christoph, Faust, Sabrina K, Vicinus, Benjamin, Gräber, Stefan, Kollmar, Otto, Schilling, Martin K
Format: Artigo
Sprache:Inglês
Veröffentlicht: BioMed Central 2011
Schlagworte:
Research
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3049756/
https://ncbi.nlm.nih.gov/pubmed/21349176
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1479-5876-9-22
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