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Comparison of methods for handling missing data on immunohistochemical markers in survival analysis of breast cancer

BACKGROUND: Tissue micro-arrays (TMAs) are increasingly used to generate data of the molecular phenotype of tumours in clinical epidemiology studies, such as studies of disease prognosis. However, TMA data are particularly prone to missingness. A variety of methods to deal with missing data are avai...

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Detalhes bibliográficos
Main Authors: Ali, A M G, Dawson, S-J, Blows, F M, Provenzano, E, Ellis, I O, Baglietto, L, Huntsman, D, Caldas, C, Pharoah, P D
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3049587/
https://ncbi.nlm.nih.gov/pubmed/21266980
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjc.6606078
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