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Characterization of five partial deletions of the factor VIII gene.

Hemophilia A is an X-linked disorder of coagulation caused by a deficiency of factor VIII. By using cloned DNA probes, we have characterized the following five different partial deletions of the factor VIII gene from a panel of 83 patients with hemophilia A: (i) a 7-kilobase (kb) deletion that elimi...

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Udgivet i:Proc Natl Acad Sci U S A
Principais autores: Youssoufian, H, Antonarakis, S E, Aronis, S, Tsiftis, G, Phillips, D G, Kazazian, H H
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 1987
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC304958/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/3035554/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.84.11.3772
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