Enhanced ZAG production by subcutaneous adipose tissue is linked to weight loss in gastrointestinal cancer patients

BACKGROUND: Profound loss of adipose tissue is a hallmark of cancer cachexia. Zinc-α2-glycoprotein (ZAG), a recently identified adipokine, is suggested as a candidate in lipid catabolism. METHODS: In the first study, eight weight-stable and 17 cachectic cancer patients (weight loss ⩾5% in previous 6...

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Autors principals: Mracek, T, Stephens, N A, Gao, D, Bao, Y, Ross, J A, Rydén, M, Arner, P, Trayhurn, P, Fearon, K C H, Bing, C
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group 2011
Matèries:
Translational Therapeutics
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3049573/
https://ncbi.nlm.nih.gov/pubmed/21245862
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjc.6606083
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