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Silibinin Inhibits Human Non-small Cell Lung Cancer Cell Growth through Cell Cycle Arrest by Modulating Expression and Function of Key Cell Cycle Regulators

Recent studies show that silibinin possesses a strong anti-neoplastic potential against many cancers; however, its efficacy and underlying molecular mechanisms in non-small cell lung cancer (NSCLC) are not well-defined. Herein, we assessed silibinin activity on prime endpoints and key molecular targ...

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Detalhes bibliográficos
Main Authors: Mateen, Samiha, Tyagi, Alpna, Agarwal, Chapla, Singh, Rana P., Agarwal, Rajesh
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3049548/
https://ncbi.nlm.nih.gov/pubmed/19908243
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/mc.20595
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