Noninvasive and localized blood–brain barrier disruption using focused ultrasound can be achieved at short pulse lengths and low pulse repetition frequencies

Ultrasound methods in conjunction with microbubbles have been used for brain drug delivery, treatment of stroke, and imaging of cerebral blood flow. Despite advances in these areas, questions remain regarding the range of ultrasound parameters that disrupt the blood–brain barrier (BBB). In this stud...

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Библиографические подробности
Главные авторы: Choi, James J, Selert, Kirsten, Gao, Zimeng, Samiotaki, Gesthimani, Baseri, Babak, Konofagou, Elisa E
Формат: Artigo
Язык:Inglês
Опубликовано: Nature Publishing Group 2011
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Original Article
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC3049526/
https://ncbi.nlm.nih.gov/pubmed/20842160
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/jcbfm.2010.155
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