Metabolic acidosis induced by Plasmodium falciparum intraerythrocytic stages alters blood–brain barrier integrity

The pathogenesis of cerebral malaria (CM) remains largely unknown. There is growing evidence that combination of both parasite and host factors could be involved in blood–brain barrier (BBB) breakdown. However, lack of adequate in vitro model of human BBB so far hampered molecular studies. In this a...

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Bibliographische Detailangaben
Hauptverfasser: Zougbédé, Sergine, Miller, Florence, Ravassard, Philippe, Rebollo, Angelita, Cicéron, Liliane, Couraud, Pierre-Olivier, Mazier, Dominique, Moreno, Alicia
Format: Artigo
Sprache:Inglês
Veröffentlicht: Nature Publishing Group 2011
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Original Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3049507/
https://ncbi.nlm.nih.gov/pubmed/20683453
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/jcbfm.2010.121
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