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The human transforming growth factor type alpha coding sequence is not a direct-acting oncogene when overexpressed in NIH 3T3 cells.

A peptide secreted by some tumor cells in vitro imparts anchorage-independent growth to normal rat kidney (NRK) cells and has been termed transforming growth factor type alpha (TGF-alpha). To directly investigate the transforming properties of this factor, the human sequence coding for TGF-alpha was...

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Bibliografske podrobnosti
izdano v:Proc Natl Acad Sci U S A
Main Authors: Finzi, E, Fleming, T, Segatto, O, Pennington, C Y, Bringman, T S, Derynck, R, Aaronson, S A
Format: Artigo
Jezik:Inglês
Izdano: National Academy of Sciences 1987
Teme:
Online dostop:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC304950/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/3035551/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.84.11.3733
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