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miR-31 modulates dystrophin expression: new implications for Duchenne muscular dystrophy therapy

Duchenne muscular dystrophy (DMD)—which is caused by mutations in the dystrophin gene—is one of the most severe myopathies. Among therapeutic strategies, exon skipping allows the rescue of dystrophin synthesis through the production of a shorter but functional messenger RNA. Here, we report the iden...

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Detalhes bibliográficos
Main Authors: Cacchiarelli, Davide, Incitti, Tania, Martone, Julie, Cesana, Marcella, Cazzella, Valentina, Santini, Tiziana, Sthandier, Olga, Bozzoni, Irene
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3049433/
https://ncbi.nlm.nih.gov/pubmed/21212803
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/embor.2010.208
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