The biological activity of FasL in human and mouse lungs is determined by the structure of its stalk region

Acute lung injury (ALI) is a life-threatening condition in critically ill patients. Injury to the alveolar epithelium is a critical event in ALI, and accumulating evidence suggests that it is linked to proapoptotic Fas/FasL signals. Active soluble FasL (sFasL) is detectable in the bronchoalveolar la...

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Hlavní autoři: Herrero, Raquel, Kajikawa, Osamu, Matute-Bello, Gustavo, Wang, Yi, Hagimoto, Naoki, Mongovin, Steve, Wong, Venus, Park, David R., Brot, Nathan, Heinecke, Jay W., Rosen, Henry, Goodman, Richard B., Fu, Xiaoyun, Martin, Thomas R.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Clinical Investigation 2011
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Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3049393/
https://ncbi.nlm.nih.gov/pubmed/21285513
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI43004
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