An N-terminal truncated carboxypeptidase E splice isoform induces tumor growth and is a biomarker for predicting future metastasis in human cancers

Metastasis is a major cause of mortality in cancer patients. However, the mechanisms governing the metastatic process remain elusive, and few accurate biomarkers exist for predicting whether metastasis will occur, something that would be invaluable for guiding therapy. We report here that the carbox...

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Autores principales: Lee, Terence K., Murthy, Saravana R.K., Cawley, Niamh X., Dhanvantari, Savita, Hewitt, Stephen M., Lou, Hong, Lau, Tracy, Ma, Stephanie, Huynh, Thanh, Wesley, Robert A., Ng, Irene O., Pacak, Karel, Poon, Ronnie T., Loh, Y. Peng
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Clinical Investigation 2011
Materias:
Research Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3049392/
https://ncbi.nlm.nih.gov/pubmed/21285511
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI40433
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